ECLIPSE Serotonin Catalyst Caps
Precursor Optimization. Not Replacement.
ECLIPSE — Serotonin Catalyst Caps
CORE PROTOCOL
Precursor Optimization. Not Hormone Replacement. Know the Difference.
The Mechanism of Action
Exogenous melatonin is the crutch of the uninformed biohacker. Directly introducing a synthetic hormone at 3–10mg—when the body’s natural nocturnal surge is approximately 0.3mg—downregulates pineal function with chronic use, creates dependency patterns, and produces next-day cognitive fog. You are replacing a system instead of optimizing it. That is the opposite of biohacking.
ECLIPSE takes the advanced approach: precursor-based circadian optimization via 5-Hydroxytryptophan (5-HTP), the immediate biochemical precursor to serotonin. Unlike dietary tryptophan, 5-HTP crosses the blood-brain barrier without requiring competitive active transport via the Large Neutral Amino Acid Transporter. Reliable CNS delivery. No dietary interference.
The circadian cascade: 5-HTP converts to serotonin via aromatic L-amino acid decarboxylase within 30–60 minutes. As darkness cues activate pineal AANAT enzyme activity, serotonin undergoes acetylation and methylation to produce melatonin endogenously—2–4 hours later. Your body manufactures the exact amount it needs, at the exact time it needs it, preserving endogenous regulatory mechanisms.
This approach preserves pineal function. Supports evening serotonergic tone for stress regulation and cognitive wind-down. Aligns with circadian darkness cues rather than overriding them. Suitable for long-term optimization without dependency.
50mg per capsule. Pharmaceutical-grade, derived from Griffonia simplicifolia seed extract. Cofactor-compatible with B6 (provided in mid-day REACH protocol).
The Operational Shift
Reduced sleep onset latency (15–30 min reduction reported). Enhanced subjective sleep quality without morning grogginess. Eliminated evening rumination and cortisol persistence from high-stakes decision processing. Restored circadian alignment that compounds nightly.
This is Swiss longevity clinic thinking applied to your PM stack. Optimization over replacement. Pathway support over pathway override. Protocol sophistication that signals exactly where you sit on the biohacking hierarchy.
CORE PROTOCOL | 2–3 hours pre-sleep, empty stomach or with light carbs | Stack with RECALIBRATE.
Circadian Precision. Endogenous Production. System Preserved.
Ingredients: Calcium (as Calcium Carbonate), 5-Hydroxytryptophan (from Griffo via simplicifolia seed extract), Gelatin (capsule), Magnesium Stearate.
Manufacturer Country: USA
Product Amount: 60 caps
Gross Weight: 0.25lb (113g)
Suggested Use: Take two (2) capsules once a day as a dietary supplement. For best results, take 20-30 min before a meal with an 8oz (236 ml) glass of water or as directed by your healthcare professional.
Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

The Science
How It Works
Clinical Research
5-HTP and Serotonin Synthesis
Research on tryptophan metabolism pathways
5-HTP crosses the blood-brain barrier and converts directly to serotonin without competition from other amino acids. Supplementation increases both serotonin and downstream melatonin levels.
Sleep and Mood Benefits
Clinical trials on 5-HTP supplementation
5-HTP (50-300mg) improved sleep onset, sleep quality, and mood scores in multiple controlled trials. Unlike direct melatonin, it supports endogenous production without suppressing natural synthesis.